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Shell is degradation product of chitosan oligosaccharide, small molecular weight, soluble in water, can be absorbed by the human, animal and plant body to use, the study found that the shell and chitosan oligosaccharide not only has some similar properties, nature and some physiological activity or function even more significant. Studies have shown that chitosan has obvious hypoglycemic effect, which can enhance the glucose tolerance of human body, improve the function of islet cells, and increase the tendency of in blood. The hypoglycemic effect of chitosan may be related to receptors, which can increase the sensitivity of receptors, thus controlling the increase of blood glucose.